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IUPAC: 2-diphenylmethanesulfinyl-N-hydroxyacetamide

CAS: 63547-13-7

Molecular Formula: C15H15NO3S

Molecular Weight: 289.351

Form: Powder - Crystal


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Adrafinil is a fairly potent eugeroic compound that is often prescribed to combat fatigue and difficulty maintaining attention. It is not FDA-approved as a medicinal drug in the US, but it is currently unregulated there.

Known side effects include anxiety, stomach pain and skin irritation.

The full chemical name for Adrafinil is (RS)-2-benzhydrylsulfinylethanehydroxamic acid, and its chemical formula is C15H15NO3S. It was discovered in France in the 1970s, and was being used to treat narcolepsy there as early as 1986.

Adrafinil is believed to act as an α1-adrenergic receptor agonist, but despite the chemical’s long history, there is much contention as to how it actually works.


Adrafinil is sold as Olmifon in Europe, and was heavily marketed in France under that name until 2011, when French medical authorities withdrew permission to market the substance, citing a poor risk to benefit ratio.It is still available by prescription in Australia.Adrafinil is completely unregulated in the USA, and it can be purchased, imported and possessed freely. It is prohibited for use by professional athletes by the World Anti-Doping Agency.

Despite its availability, Adrafinil is chiefly a research chemical. It should not be taken by humans in the absence of a prescription or recommendation from a practicing health professional. 

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